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It depends on the dosage and speed of metabolism:

Acetylsalicylic acid: intravenous (IV) application acts immediately. Orally, 500mg and 100 mg doses act reliably within 15 minutes (package insert Aspirin®, Bayer AG)

Clopidogrel: 2 – 6 hours after loading dose, dependent on the dosage (800 mg 2 hours, 300 mg min. 6 hours)

Prasugrel and ticagrelor: In general, acts after 30 minutes; it could be delayed if intestinal absorption is delayed (e.g. by other medications).

Cangrelor: Intravenous administration acts after 2 minutes.

References:

1. Bayer AG. Aspirin: Instructions for Use (IFU). Leverkusen: Bayer GmbH.

2. Sanofi, Bristol-Myers Squibb. Plavix: Instructions for Use (IFU). Sanofi & BMS.

3. Eli Lilly and Company. Effient: Instructions for Use (IFU). Indianapolis: Eli Lilly.

4. AstraZeneca. Brilinta: Instructions for Use (IFU). Cambridge: AstraZeneca.

5. Chiesi Farmaceutici S.p.A. Kengreal: Instructions for Use (IFU). Parma: Chiesi Farmaceutici S.p.A.

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