IMPACT U46619 reagent is used to detect platelet dysfunction, or normal platelet activity in human whole blood.It can be utilized to test for thromboxane and cyclooxygenase receptor abnormalities.

Thromboxane A2 (TXA2) is generated from Prostaglandin H2 by enzyme thromboxane-A synthase.

IMPACT U46619 is utilised as it is a stable analog of TXA2, exhibiting similar properties to the receptor agonist, inducing platelet aggregation and vascular smooth muscle contraction.

Can be utilized to test for thromboxane and cyclooxygenase receptor abnormalities.